| Инд. авторы: | Kolpakov F., Akberdin I., Kashapov T., Kiselev I., Kolmykov S., Kondrakhin Y., Kutumova E., Mandrik N., Pintus S., Ryabova A., Sharipov R.N., Yevshin I., Kel A. |
| Заглавие: | BioUML: an integrated environment for systems biology and collaborative analysis of biomedical data |
| Библ. ссылка: | Kolpakov F., Akberdin I., Kashapov T., Kiselev I., Kolmykov S., Kondrakhin Y., Kutumova E., Mandrik N., Pintus S., Ryabova A., Sharipov R.N., Yevshin I., Kel A. BioUML: an integrated environment for systems biology and collaborative analysis of biomedical data // Nucleic Acids Research. - 2019. - Vol.47. - Iss. W1. - P.W225-W233. - ISSN 0305-1048. - EISSN 1362-4962. |
| Внешние системы: | DOI: 10.1093/nar/gkz440; РИНЦ: 43204438; PubMed: 31131402; SCOPUS: 2-s2.0-85069238519; WoS: 000475901600032; |
| Реферат: | eng: BioUML (homepage: http://www.biouml.org, main public server: https://ict.biouml.org) is a web-based integrated environment (platform) for systems biology and the analysis of biomedical data generated by omics technologies. The BioUML vision is to provide a computational platform to build virtual cell, virtual physiological human and virtual patient. BioUML spans a comprehensive range of capabilities, including access to biological databases, powerful tools for systems biology (visual modelling, simulation, parameters fitting and analyses), a genome browser, scripting (R, JavaScript) and a workflow engine. Due to integration with the Galaxy platform and R/Bioconductor, BioUML provides powerful possibilities for the analyses of omics data. The plug-in-based architecture allows the user to add new functionalities using plug-ins. To facilitate a user focus on a particular task or database, we have developed several predefined perspectives that display only those web interface elements that are needed for a specific task. To support collaborative work on scientific projects, there is a central authentication and authorization system (https://bio-store.org). The diagram editor enables several remote users to simultaneously edit diagrams.
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| Ключевые слова: | CIRCULATION; TOOL; SOFTWARE; MODULAR MODEL; STOCHASTIC SIMULATION; FACTOR-BINDING SITES; GENENET; |
| Издано: | 2019 |
